Determining the Antioxidant Efficacy of ASEA Redox Supplement

Oxidative damage has been implicated in aging and age-dependent diseases, including cardiovascular disease, cancer, neurodegenerative disorders, and other chronic conditions. If the generation of free radicals exceeds the protective effects of antioxidants and some co-factors, this can cause oxidative damage.

Glutathione peroxidase (GPx) is an essential enzyme in cellular antioxidant defense systems, detoxifying peroxides and hydroperoxides. Superoxide dismutase (SOD) is an enzyme that helps break down potentially harmful oxygen molecules in cells, which might prevent damage to tissues.

In this study, scientists attempted to determine if direct contact of ASEA Redox Supplement to cells affects the antioxidant efficacy of GPx and SOD.

Study Protocol

Cultures of standard epidermal cells were exposed to various small concentrations of ASEA Redox Supplement (less than 1%) and a phosphate buffered saline (PBS) solution for 24 hours. The decrease of oxidants due to GPx enzymatic activity was monitored over an eleven-minute period after a chemical agent (cumene hydroperoxide) initiated the reaction. The reduction of oxidants is an indication of antioxidant efficacy. Three replications of oxidant residual in the samples were read every two minutes to determine GPx efficacy at various concentrations of PBS or ASEA Redox Supplement.

Results Summary

An 800% increase in GPx antioxidant efficacy was seen after 24 hours of exposure from low concentration ASEA Redox Supplement. A transitory increase of up to 500% was observed in SOD antioxidant efficacy between 30 and 90 minutes after exposure to low-concentration ASEA Redox Supplement (< 1%).

Exposure to high concentration ASEA Redox Supplement, in comparison, elicited only a small relative increase in GPx antioxidant efficacy that was not concentration dependent. An increase in SOD efficacy was not seen for either high concentration ASEA Redox Supplement or after long exposures (24 hours).


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